Application Of Transgenic Animals Wikipedia

Applications Transgenic models for Alzheimer disease amyotrophic lateral sclerosis Huntington disease arthritis muscular dystrophy tumorigenesis hypertension neurodegenerative disorders endocrinological dysfunction coronary disease etc.

Application of transgenic animals wikipedia. Clotting factors vaccines monocl onal antibodies growth factors collagen fibrinogen. Applications of Transgenic Animals 1 Can use gene transfer to improve the productivity of livestock. 1 Resistance to Biotic Stresses 2 Resistance to Abiotic Stresses 3 Improvement of Crop Yield and Quality 4 Transgenic Plants with Improved Nutrition5 Commercial Transgenic Crop Plants and 6 Transgenic Plants as Bioreactors.

Transgenesis is the process by which mixing up of genes takes place. They provide genetic models of va rious human d. I to obtain information on gene function and regulation as well as on human diseases ii to obtain high value products recombinant pharmaceutica.

Transgenic animals are those that have been genetically modified. This is a brighter look for our future industrial wise. However the realization of genetically engineered livestock has been much slower.

Theoretically all living beings can be genetically manipulated. The application of transgenic animals showed that within the next five to eight years genetically modified animals will play a significant and important role in the biomedical field in particular via the production of valuable pharmaceutical proteins and the supply of xenografts. The production of transgenic animals has focused mainly on producing models eg the mouse for basic and medical research.

Applications of animal transgenesis may be divided into three major categories. A transgenic animal is one that carries a foreign gene that has been deliberately inserted into its genome. One favoured method involves the inoculation of the DNA into the pronucleus of a fertilised ovum followed by implantation into pseudo pregnant females.

These animals can be helpful in producing organs growth hormones and useful proteins for the humans. This not only enables several human diseases to be cured but also make many people. This results in a proportion of animals carrying the transgene in the germ line which may be high in some species eg.